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''''''{{Infobox protein family| Symbol = 顺乌头酸酶'''<ref>| Name = 顺乌头酸酶家族{{PDB|1ACO}}; {{cite journal |pages=437–51 |doi=10.1006/jmbi.1994.1246 |title=Crystal Structures of Aconitase with Trans-aconitate and Nitrocitrate Bound |year=1994 |last1=Lauble |first1=H |journal=Journal of Molecular Biology |volume=237 |issue=4 |pmid=8151704 |last2=Kennedy |first2=MC |last3=Beinert |first3=H |last4=Stout |first4=CD}}[http://www.term.gov.cn/pages/homepage/result2.jsp?id=332348&subid=10001798&subject=%E9%85%B6&subsys=%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E4%B8%8E%E5%88%86%E5%AD%90%E7%94%9F%E7%89%A9%E5%AD%A6]</ref>'''（，简称为'''[[乌头酸]]酶'''，）是一种在三[[羧酸]]循[[环中]][[催化]][[柠檬酸]]通过顺乌头酸中间步骤[[立体专一性]]可逆异构化为[[异柠檬酸]]的酶，这是一个非[[氧化还原]]步骤<ref name{{cite journal |pmid=8262329 |year=1993 |last1=Beinert |first1=H |last2=Kennedy |first2=MC |title=Aconitase, a two-faced protein: Enzyme and iron regulatory factor |volume=7 |issue="pmid8262329"></ref><ref name15 |pages="pmid11848829"></ref><ref name1442–9 |journal="pmid11848830"></ref>The FASEB journal}}。

<gallery>  Image:Citrate wpmp.png|<center>柠檬酸</center> Image:Cis-Aconitate wpmp.png|<center>乌头酸</center> Image:Threo-Ds-isocitrate wpmp.png|<center>异柠檬酸</center> </gallery>柠檬酸乌头酸异柠檬酸

| {{protein| Name = 顺乌头酸酶1，可溶性| caption = | image = | width = | HGNCid = 117| Symbol = ACO1| AltSymbols = IREB1| EntrezGene = 48| OMIM = 100880| RefSeq = NM_002197| UniProt = P21399| PDB = | ECnumber = 4.2.1.3| Chromosome = 9| Arm = p| Band = 21.1| LocusSupplementaryData = }}| {{protein| Name = 顺乌头酸酶2，线粒体酶| caption = | image = | width = | HGNCid = 118| Symbol = ACO2| AltSymbols = ACONM| EntrezGene = 50| OMIM = 100850| RefSeq = NM_001098| UniProt = Q99798| PDB = | ECnumber = 4.2.1.3| Chromosome = 22| Arm = q| Band = 13.2| LocusSupplementaryData = }}

* {{MeshName|Aconitase}}* {{Proteopedia|Aconitase}} - the Aconitase structure in interactive 3D