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在人类[[细胞]]内，大约有1%的DNA碱基受到了[[甲基化]]。在成熟体[[细胞组织]]中，DNA甲基化一般发生于[[CpG位置|CpG]]双[[核苷酸]]（CpG dinucleotide）部位；而非CpG甲基化则于[[胚胎干细胞]]中较为常见
。植物体内胞嘧啶的甲基化则可分为对称的CpG（或CpNpG），或是不对称的CpNpNp形式（C与G是碱基；p是[[磷酸根]]；N指的是任意的核苷酸）。
== 延伸阅读 ==
* Elias Daura-Oller, Maria Cabre, Miguel A Montero, Jose L Paternain, and Antoni Romeu (2009)"Specific gene hypomethylation and cancer: New insights into coding region feature trends". Bioinformation. 2009; 3(8): 340–343.PMID PMC2720671 * Shen, L. & Waterland, R.A. (2008): ''Methods of DNA methylation analysis.'' In: ''Curr. Opin. Clin. Nutr. Metab. Care.'' 10(5):576–581. PMID 17693740 * Beck, S. & Rakyan, V.K. (2008): ''The methylome: approaches for global DNA methylation profiling.'' In: ''Trends Genet.'' 24(5):231–237. PMID 18325624
* Shames, D.S. et al.'' (2007): ''DNA methylation in health, disease, and cancer.'' In: ''Curr. Mol. Med.'' 7(1):85–102. PMID 17311535 [http://bentham.org/cmm/sample/cmm7-1/0008M.pdf PDF]
* Patra, S. K. (2008) Ras regulation of DNA-methylation and cancer. Exp Cell Res 314(6): 1193-1201.
== 外部连结 ==
*[http://www.methdb.net/ DNA Methylation database]
*
[[Category:DNA]]
