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#^ Kool ET (1984). \"Active site tightness and substrate fit in DNA replication\". Annual Review of Biochemistry 71: 191–219. doi:10.1146/annurev.biochem.71.110601.135453.#^ a b Sullivan SM (2008). \"Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection\". Proceedings of the National Academy of Sciences of the United States of America 105: 13829–13834. doi:10.1073/pnas.0805364105.#^ a b Schechter I (2005). \"Mapping of the active site of proteases in the 1960s and rational design of inhibitors/drugs in the 1990s\". Current Protein and Peptide Science 6: 501–512. doi:10.2174/138920305774933286.#^ a b c DeDecker BS (2000). \"Allosteric drugs: thinking outside the active-site box\". Chemistry and Biology 7: 103–107. doi:10.1016/S1074-5521(00)00115-0.#^ Zuercher M (2008). \"Structure-Based Drug Design: Exploring the Proper Filling of Apolar Pockets at Enzyme Active Sites\". Journal of Organic Chemistry 73: 4345–4361. doi:10.1021/jo800527n.#^ Powers R (2006). \"Comparison of protein active site structures for functional annotation of proteiproteins and drug design". Proteins - Structure, Function and Bioinformatics 65: 124–135. doi:10.1002/prot.21092.    [[Category:酶]] [[Category:催化]]==参考来源==*[http://zh.wikipedia.org/wiki/%E6%B4%BB%E6%80%A7%E4%BD%8D%E7%82%B9 维基百科-活性位点]